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魏雪锋

时间:2018-10-16 16:09:33  点击:   发布者:skyJX

 



职称:副教授

学位:农学博士

专业:动物遗传育种与繁殖

办公室:综合楼实验楼 博士工作室

联系方式: weixuefeng.happy@163.com

 

 

教育经历

2013-2017 西北农林科技大学动物科技学院,农学博士

2010-2013云南农业大学动物科技学院,农学硕士

2006-2010湖州师范学院新葡的京集团8814,理学学士

工作经历

2017.09- 至今 信阳师范学院 新葡的京集团8814  讲师

教学情况

主讲课程:本科生课程《遗传学》、《实验动物学》、《生物技术制药》,研究生课程《表观遗传学》、《生物发展史》

研究领域

家畜肌肉组织发育和脂肪沉积的重要基因挖掘及分子调控机理研究,主要关注肌肉和脂肪相关功能基因、非编码RNA miRNA、circRNA功能、互作及调控机制。

主持科研项目

主持国家自然科学基金青年项目,信阳师范学院高层次人才科研启动基金项目共2项,参与中原科技创新领军人才项目1项;

1.    国家自然科学基金青年项目,“牛CircMYBPC1调控肌原代细胞增殖、分化的分子机制解析”,2019.01-2021.12,27万,在研,主持。

2.    信阳师范学院高层次人才科研启动基金项目,“长链非编码RNA调控牛肌细胞增殖分化的分子机制研究”,在研,主持。

发表论文

1、Xuefeng Wei, Hui Li, Bowen Zhang, ... & Hong Chen*. miR-378a-3p promotes differentiation and inhibits proliferation of myoblasts by targeting HDAC4 in skeletal muscle development. RNA Biology, 2016, 13(12): 1300-1309.

2、Xuefeng Wei, Hui Li, Jiameng Yang, ... & Hong Chen*. Circular RNA profiling reveals an abundant circLMO7 that regulates myoblasts differentiation and survival by sponging miR-378a-3p. Cell Death & Disease. 2017, 8(10): e3153.

3、Xuefeng Wei, Hui Li, Guangwei Zhao, ... & Hong Chen*. ΔFosB regulates rosiglitazone-induced milk fat synthesis and cell survival. Journal of cellular physiology, 2017, 11.20. DOI:10.1002/jcp.26218.

4、Hui Li#, Xuefeng Wei#, Jiameng Yang, ... & Hong Chen*. circFGFR4 Promotes Differentiation of Myoblasts via Binding miR-107 to Relieve Its Inhibition of Wnt3a. Molecular Therapy-Nucleic Acids, 2018, 11: 272-283. (#,co-first)

5、Hui Li#, Xuefeng Wei#, Jiameng Yang, ... & Hong Chen*. Development transcriptome profiling of bovine muscle tissue reveals an aboundant GosB the regulates myoblasts proliferation and apoptosis. Oncotarget, 2017, 8(19):32083-32100.

6、Hui Li#, Jiameng Yang#, Xuefeng Wei#, Chengchuang Song, ... & Hong Chen*. CircFUT10 reduces proliferation and facilitates differentiation of myoblasts by sponging miR-133a. Journal of cellular physiology, 2018, 233(6): 4643-4651.

7、Xuefeng Wei, Shuang Han, Shuzhe Wang ... Yun Ma. ANGPTL8 regulates adipocytes differentiation and adipogenesis in bovine. Gene, 2019, 707: 93-99.

8、Xuefeng Wei, Yunchang Zhu, Jie Du ... Yun Ma. Analysis of ANGPTL8 promoter activity and screening of related transcription factors in bovine. Gene, 2021, 784: 145594.

9、Mengjie Chen,# Xuefeng Wei,# Mingming Song, ... & Hui Li*. Circular RNA circMYBPC1 promotes skeletal muscle differentiation by targeting MyHC. Molecular Therapy-Nucleic Acids, 2021, 24: 352-368. (#,co-first)

10、    Bowen Zhang, Hanfang Cai, Xuefeng Wei, Jiajie Sun, ... & Hong Chen. MiR-30-5p Regulates Muscle Differentiation and Alternative Splicing of Muscle-Related Genes by Targeting MBNL. International Journal of Molecular Sciences. 2016, 17(2), 182.

11、    Mingxun Li, Xiaomei Sun, Yang Zhou, Xuefeng Wei, ... & Hong Chen.  Nicotinamide  and  resveratrol  regulate  bovine  adipogenesis  through  a  SIRT1-dependent mechanism. Journal of Functional Foods 2015, 18, 492-500.

 

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